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Senolytic
Anti-Aging
FOX04-Dri
A D-retro-inverso peptide designed to selectively target senescent cells by disrupting the p53-FOXO4 interaction. A novel senolytic compound studied for aging and tissue homeostasis research.
For Research Use Only. This product is not intended for human consumption. By purchasing, you confirm this product will be used for research purposes only.
$150.00
15 in stock
1
99%+ Purity
HPLC Verified
Fast Shipping
2-3 Day Delivery
Overview
FOX04-DRI is a D-retro-inverso peptide specifically designed to disrupt the FOXO4-p53 interaction — a critical signaling axis that maintains cellular senescence. This innovative peptide has generated significant excitement in the longevity and senolytics research community.
Mechanism of Action
FOX04-DRI competitively binds to p53, preventing its sequestration by FOXO4. This restores p53's ability to trigger apoptosis selectively in senescent cells while sparing healthy cells. Published research in Cell demonstrated improvements in physical fitness, renal function, and tissue quality in aged models.
Research Applications
- Senolytics — selective elimination of senescent cells
- Aging reversal — healthspan extension studies
- Tissue rejuvenation — organ function restoration in aged models
- Senescence biology — understanding FOXO4-p53 signaling
- D-retro-inverso peptides — enhanced proteolytic stability research
Product Details
- Purity: ≥98% (HPLC verified)
- Form: Lyophilized powder (D-retro-inverso modified)
- Analysis: HPLC and mass spectrometry
- Storage: Store at -20°C for long-term stability
For research use only — not for human consumption.
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